بررسی میزان نقایص لوله عصبی و فاکتورهای موثر در بروز آن در زمان لقاح در زنان باردار

Authors

  • M. Javanmard, M.Sc,
  • دکتر غلامرضا بابائی ملیحه جوانمرد,
  • مریم کشاورز,
Abstract:

Introduction & Objective: After cardiac defects, neural–tube defects (NTD) are the most congenital structural defects with a worldwide incidence of 1.4 to 2 per 1000 live births. This defect is due to failure of the neural tube to close spontaneously between the 3rd and 4th wk of uterine development. The control of risk factors related to NTD, decreases the  psychologic  problems  and it is cost effect. Materials & Methods: Of 14588 women that referred to delivery room in Fatemiyeh  Hospital from March 1998 until Sep 2002, 55 women had fetus or neonate with NTD (case group). 100 women with normal neonate in a systematic randomized  sampling were chosen as a control group. Results: During 4.5 years, 55 women (3.7 in 1000) had fetus or neonate with NTD. Between two groups there were statistical difference in the rate of hydramniose during pregnancy )p<0.001, OR=0.045 CI=0.005-0.3) and sever fever (p=0.001,OR=0.05 CI=0.006-0.44)) around the conception’s time and early pregnancy. There were no statistical difference between two groups in folic acid consuming. Conclusion: In recent years, many studies were carried out for survey of folic acid deficiency on NTD. In this research both groups consumed folic acid from the third month of pregnancy and there was no difference in consuming of the folic acid supplement between two groups. The NTD development is between the 3rd and 4th week of pregnancy, so intake of 400µcg folic acid daily (according to CDC and ACOG recommendations) in all women in reproductive age that referred to health care setting is offered, also notice to the fever around the ovulation time as an effective factor in decrease incidence of NTD is important.   

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

بررسی میزان نقایص لوله عصبی و فاکتورهای موثر در بروز آن در زنان باردار مراجعه کننده به زایشگاه فاطمیه شاهرود

سابقه و هدف: نقایص لوله عصبی پس از نقایص قلبی شایعترین ناهنجاریهای مادرزادی به شمار می روند. میزان بروز آنها 1.4-2 در هر 1000 تولد زنده است. این نقایص ناشی از اختلال در بسته شدن لوله عصبی در هفته سوم و چهارم زندگی جنینی است. شناسایی و آموزش پیشگیری از عوامل خطرزا اهمیت زیادی داشته و از بسیاری از مشکلات عاطفی مادر و تحمیل هزینه ها پیشگیری می نماید.روش بررسی: در یک مطالعه مورد شاهدی، از میان کلیه...

full text

بررسی میزان نقایص لوله عصبی و فاکتورهای موثر در بروز آن در زنان باردار مراجعه کننده به زایشگاه فاطمیه شاهرود

سابقه و هدف: نقایص لوله عصبی پس از نقایص قلبی شایعترین ناهنجاریهای مادرزادی به شمار می روند. میزان بروز آنها 1.4-2 در هر 1000 تولد زنده است. این نقایص ناشی از اختلال در بسته شدن لوله عصبی در هفته سوم و چهارم زندگی جنینی است. شناسایی و آموزش پیشگیری از عوامل خطرزا اهمیت زیادی داشته و از بسیاری از مشکلات عاطفی مادر و تحمیل هزینه ها پیشگیری می نماید.روش بررسی: در یک مطالعه مورد شاهدی، از میان کلیه...

full text

اثر بربرین در تنظیم آستروسیتهای Gfap+ ناحیه هیپوکمپ موشهای صحرایی دیابتی شده با استرپتوزوتوسین

Background: Diabetes mellitus increases the risk of central nervous system (CNS) disorders such as stroke, seizures, dementia, and cognitive impairment. Berberine, a natural isoquinolne alkaloid, is reported to exhibit beneficial effect in various neurodegenerative and neuropsychiatric disorders. Moreover astrocytes are proving critical for normal CNS function, and alterations in their activity...

full text

اثر بربرین در تنظیم آستروسیتهای Gfap+ ناحیه هیپوکمپ موشهای صحرایی دیابتی شده با استرپتوزوتوسین

Background: Diabetes mellitus increases the risk of central nervous system (CNS) disorders such as stroke, seizures, dementia, and cognitive impairment. Berberine, a natural isoquinolne alkaloid, is reported to exhibit beneficial effect in various neurodegenerative and neuropsychiatric disorders. Moreover astrocytes are proving critical for normal CNS function, and alterations in their activity...

full text

Degenerate Four Wave Mixing in Photonic Crystal Fibers

In this study, Four Wave Mixing (FWM) characteristics in photonic crystal fibers are investigated. The effect of channel spacing, phase mismatching, and fiber length on FWM efficiency have been studied. The variation of idler frequency which obtained by this technique with pumping and signal wavelengths has been discussed. The effect of fiber dispersion has been taken into account; we obtain th...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 13  issue 2

pages  1- 11

publication date 2006-01

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

No Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023